Goodman and Gilman Manual of Pharmacology and Therapeutics

Preface

Section I. General Principles

CHAPTER 1. Drug Invention and the Pharmaceutical Industry

CHAPTER 2. Pharmacokinetics: The Dynamics of Drug Absorption, Distribution, Metabolism, and Elimination

CHAPTER 3. Pharmacodynamics: Molecular Mechanisms of Drug Action

CHAPTER 4. Drug Toxicity and Poisoning

CHAPTER 5. Membrane Transporters and Drug Response

CHAPTER 6. Drug Metabolism

CHAPTER 7. Pharmacogenetics

Section II. Neuropharmacology

CHAPTER 8. Neurotransmission: The Autonomic and Somatic Motor Nervous Systems

CHAPTER 9. Muscarinic Receptor Agonists and Antagonists

CHAPTER 10. Anticholinesterase Agents

CHAPTER 11. Agents Acting at the Neuromuscular Junction and Autonomic Ganglia

CHAPTER 12. Adrenergic Agonists and Antagonists

CHAPTER 13. 5-Hydroxytryptamine (Serotonin) and Dopamine

CHAPTER 14. Neurotransmission and the Central Nervous System

CHAPTER 15. Drug Therapy of Depression and Anxiety Disorders

CHAPTER 16. Pharmacotherapy of Psychosis and Mania

CHAPTER 17. Hypnotics and Sedatives

CHAPTER 18. Opioids, Analgesia, and Pain Management

CHAPTER 19. General Anesthetics and Therapeutic Gases

CHAPTER 20. Local Anesthetics

CHAPTER 21. Pharmacotherapy of the Epilepsies

CHAPTER 22. Treatment of Central Nervous System Degenerative Disorders

CHAPTER 23. Ethanol and Methanol

CHAPTER 24. Drug Addiction

Section III. Modulation of Cardiovascular Function

CHAPTER 25. Regulation of Renal Function and Vascular Volume

CHAPTER 26. Renin and Angiotensin

CHAPTER 27. Treatment of Myocardial Ischemia and Hypertension

CHAPTER 28. Pharmacotherapy of Congestive Heart Failure

CHAPTER 29. Anti-Arrhythmic Drugs

CHAPTER 30. Blood Coagulation and Anticoagulant, Fibrinolytic, and Antiplatelet Drugs

CHAPTER 31. Drug Therapy for Hypercholesterolemia and Dyslipidemia

Section IV. Inflammation, Immunomodulation, and Hematopoiesis

CHAPTER 32. Histamine, Bradykinin, and Their Antagonists

CHAPTER 33. Lipid-Derived Autacoids: Eicosanoids and Platelet-Activating Factor

CHAPTER 34. Pharmacotherapy of Inflammation, Fever, Pain, and Gout

CHAPTER 35. Immunosuppressants, Tolerogens, and Immunostimulants

CHAPTER 36. Pulmonary Pharmacology

CHAPTER 37. Hematopoietic Agents: Growth Factors, Minerals, and Vitamins

Section V. Hormones and Hormone Antagonists

CHAPTER 38. Introduction to Endocrinology: The Hypothalamic-Pituitary Axis

CHAPTER 39. Thyroid and Anti-Thyroid Drugs

CHAPTER 40. Estrogens and Progestins

CHAPTER 41. Androgens

CHAPTER 42. Pharmacology of the Adrenal Cortex

CHAPTER 43. Endocrine Pancreas and Pharmacotherapy of Diabetes Mellitus and Hypoglycemia

CHAPTER 44. Agents Affecting Mineral Ion Homeostasis and Bone Turnover

Section VI. Drugs Affecting Gastrointestinal Function

CHAPTER 45. Pharmacotherapy of Gastric Acidity, Peptic Ulcers, and Gastroesophageal Reflux Disease

CHAPTER 46. Gastrointestinal Motility and Water Flux; Emesis; Biliary and Pancreatic Disease

CHAPTER 47. Pharmacotherapy of Inflammatory Bowel Disease

Section VII. Chemotherapy of Microbial Diseases

CHAPTER 48. General Principles of Antimicrobial Therapy

CHAPTER 49. Chemotherapy of Malaria

CHAPTER 50. Chemotherapy of Protozoal Infections: Amebiasis, Giardiasis, Trichomoniasis, Trypanosomiasis, Leishmaniasis, and Other Protozoal Infections

CHAPTER 51. Chemotherapy of Helminth Infections

CHAPTER 52. Sulfonamides, Trimethoprim-Sulfamethoxazole, Quinolones, and Agents for Urinary Tract Infections

CHAPTER 53. Penicillins, Cephalosporins, and Other β-Lactam Antibiotics

CHAPTER 54. Aminoglycosides

CHAPTER 55. Protein Synthesis Inhibitors and Miscellaneous Antibacterial Agents

CHAPTER 56. Chemotherapy of Tuberculosis, Mycobacterium Avium Complex Disease, and Leprosy

CHAPTER 57. Antifungal Agents

CHAPTER 58. Antiviral Agents (Nonretroviral)

CHAPTER 59. Antiretroviral Agents and Treatment of HIV Infection

Section VIII. Chemotherapy of Neoplastic Diseases

CHAPTER 60. General Principles of Cancer Chemotherapy

CHAPTER 61. Cytotoxic Agents

CHAPTER 62. Targeted Therapies: Tyrosine Kinase Inhibitors, Monoclonal Antibodies, and Cytokines

CHAPTER 63. Natural Products in Cancer Chemotherapy: Hormones and Related Agents

Section IX. Special Systems Pharmacology

CHAPTER 64. Ocular Pharmacology

CHAPTER 65. Dermatological Pharmacology

CHAPTER 66. Contraception and Pharmacotherapy of Obstetrical and Gynecological Disorders

CHAPTER 67. Environmental Toxicology: Carcinogens and Heavy Metals

Appendix I. Principles of Prescription Order Writing and Patient Compliance