Alexander Kratz Michael A. Pesce Robert C. Basner Andrew J. Einstein
This Appendix contains tables of reference values for laboratory tests, special analytes, and special function tests. A variety of factors can influence reference values. Such variables include the population studied, the duration and means of specimen transport, laboratory methods and instrumentation, and even the type of container used for the collection of the specimen. The reference or “normal” ranges given in this appendix may therefore not be appropriate for all laboratories, and these values should only be used as general guidelines. Whenever possible, reference values provided by the laboratory performing the testing should be utilized in the interpretation of laboratory data. Values supplied in this Appendix reflect typical reference ranges in adults. Pediatric reference ranges may vary significantly from adult values.
In preparing the Appendix, the authors have taken into account the fact that the system of international units (SI, système international d’unités) is used in most countries and in some medical journals. However, clinical laboratories may continue to report values in “traditional” or conventional units. Therefore, both systems are provided in the Appendix. The dual system is also used in the text except for (1) those instances in which the numbers remain the same but only the terminology is changed (mmol/L for meq/L or IU/L for mIU/mL), when only the SI units are given; and (2) most pressure measurements (e.g., blood and cerebrospinal fluid pressures), when the traditional units (mmHg, mmH2O) are used. In all other instances in the text the SI unit is followed by the traditional unit in parentheses.
REFERENCE VALUES FOR LABORATORY TESTS
HEMATOLOGY AND COAGULATION
CLINICAL CHEMISTRY AND IMMUNOLOGY
TOXICOLOGY AND THERAPEUTIC DRUG MONITORING
VITAMINS AND SELECTED TRACE MINERALS
CLASSIFICATION OF LDL, TOTAL, AND HDL CHOLESTEROL
REFERENCE VALUES FOR SPECIFIC ANALYTES
DIFFERENTIAL NUCLEATED CELL COUNTS OF BONE MARROW ASPIRATESa
BONE MARROW CELLULARITY
URINE ANALYSIS AND RENAL FUNCTION TESTS
SPECIAL FUNCTION TESTS
NORMAL PRESSURES IN HEART AND GREAT VESSELS
CIRCULATORY FUNCTION TESTS
NORMAL ECHOCARDIOGRAPHIC REFERENCE LIMITS AND PARTITION VALUES IN ADULTS
SUMMARY OF VALUES USEFUL IN PULMONARY PHYSIOLOGY
BODY FLUIDS AND OTHER MASS DATA
The contributions of Drs. Daniel J. Fink, Patrick M. Sluss, James L. Januzzi, and Kent B. Lewandrowski to this chapter in previous editions of Harrison’s Principles of Internal Medicine are gratefully acknowledged. We also express our gratitude to Drs. Amudha Palanisamy and Scott Fink for careful review of tables and helpful suggestions.