THE APhA COMPLETE REVIEW FOR PHARMACY, 7th Ed

Appendix G: Drugs That May Cause Photosensitivity

The drugs in this table are known to cause photosensitivity in some individuals. Effects can range from itching, scaling, rash, and swelling to skin cancer, premature skin aging, skin and eye burns, cataracts, reduced immunity, blood vessel damage, and allergic reactions.

The list is not all inclusive; it shows only representative brands of each generic. When in doubt, always check specific product labeling. Individuals should be advised to wear protective clothing and to apply sunscreens while taking the following medications.

Generic name

Trade name

Acamprosate

Campral

Acetazolamide

Diamox

Acitretin

Soriatane

Acyclovir

Zovirax

Alendronate

Fosamax

Aliskiren-hydrochlorothiazide

Tekturna HCT

Alitretinoin

Panretin

Almotriptan

Axert

Amiloride-hydrochlorothiazide

Moduretic

Aminolevulinic acid

Levulan Kerastick

Amiodarone

Cordarone, Pacerone

Amitriptyline

Elavil

Amitriptyline-chlordiazepoxide

Etrafon, Limbitrol

Amitriptyline-perphenazine

 

Amlodipine-atorvastatin

Caduet

Amoxapine

Asendin

Amphetamine aspartate-amphetamine sulfate-dextroamphetamine saccharate-dextroamphetamine sulfate

Adderall XR

Anagrelide

Agrylin

Aripiprazole

Abilify

Atazanavir

Reyataz

Atenolol-chlorthalidone

Tenoretic

Atorvastatin

Lipitor

Atovaquone-proguanil

Malarone

Azatadine-pseudoephedrine

Rynatan, Trinalin

Azithromycin

Zithromax, Zmag

Benazepril

Lotensin

Benazepril-hydrochlorothiazide

Lotensin HCT

Bendroflumethiazide-nadolol

Corzide

Bexarotene

Targretin

Bismuth-metronidazole-tetracycline

Helidac

Bismuth subcitrate potassium-metronidazole-tetracycline

Pylera

Bisoprolol-hydrochlorothiazide

Ziac

Brompheniramine-dextromethorphan-phenylephrine

Alacol DM, Dimetane DX

Brompheniramine-dextromethorphan-pseudoephedrine

Bromfed-DM

Buffered aspirin-pravastatin

Pravigard PAC

Bupropion

Wellbutrin, Zyban

Candesartan-hydrochlorothiazide

Atacand HCT

Capecitabine

Xeloda

Captopril

Capoten

Captopril-hydrochlorothiazide

Capozide

Carbamazepine

Carbatrol, Equetro, Tegretol, Tegretol-XR

Carbinoxamine-pseudoephedrine

Palgic-D, Palgic-DS, Pediatex-D

Carvedilol

Coreg

Carvedilol phosphate

Coreg CR

Celecoxib

Celebrex

Cetirizine

Zyrtec

Cetirizine-pseudoephedrine

Zyrtec-D

Cevimeline

Evoxac

Chlorhexidine gluconate

Hibistat

Chloroquine

Aralen

Chlorothiazide

Diuril

Chlorothiazide sodium

Diuril I.V.

Chlorpheniramine-hydrocodone-pseudoephedrine

Tussend

Chlorpheniramine-phenylephrine

Rynatan

Chlorpromazine

Thorazine

Chlorpropamide

Diabinese

Chlorthalidone

Thalitone

Chlorthalidone-clonidine

Clorpres

Cidofovir

Vistide

Ciprofloxacin

Cipro, Cipro XR

Citalopram

Celexa

Clemastine

Tavist

Clindamycin phosphate

Clindagel

Clonidine-chlorthalidone

Clorpres

Clozapine

Clozaril, Fazzaclo

Coagulation Factor IX (recombinant)

BeneFIX

Cromolyn sodium

Gastrocrom

Cyclobenzaprine

Flexeril

Cyproheptadine

Periactin

Dacarbazine

DTIC-Dome

Dantrolene

Dantrium

Demeclocycline

Declomycin

Desipramine

Norpramin

Diclofenac potassium

Cataflam

Diclofenac sodium

Voltaren

Diclofenac sodium-misoprostol

Arthrotec

Diflunisal

Dolobid

Dihydroergotamine

D.H.E. 45

Diltiazem

Cardizem, Tiazac

Diphenhydramine

Benadryl

Divalproex

Depakote

Doxepin

Sinequan

Doxycycline hyclate

Doryx, Periostat, Vibramycin, Vibra-Tabs

Doxycycline monohydrate

Monodox

Duloxetine

Cymbalta

Efalizumab

Raptiva

Enalapril

Vasotec

Enalapril-felodipine

Lexxel

Enalapril-hydrochlorothiazide

Vaseretic

Enalaprilat (injection)

Vasotec IV

Epirubicin

Ellence

Eprosartan mesylate-hydrochlorothiazide

Teveten HCT

Erythromycin-sulfisoxazole

Pediazole

Escitalopram oxalate

Lexapro

Esomeprazole

Nexium

Estazolam

ProSom

Estradiol

Estrogel, Gynodiol

Eszopiclone

Lunesta

Ethionamide

Trecator-SC

Etodolac

Lodine

Felbamate

Felbatol

Fenofibrate

Lofibra, Tricor, Triglide

Floxuridine

Sterile FUDR

Flucytosine

Ancobon

Fluorouracil

Efudex

Fluoxetine

Prozac, Sarafem

Fluoxetine-olanzapine

Symbyax

Fluphenazine

Prolixin

Flutamide

Eulexin

Fluvastatin

Lescol, Lescol XL

Fluvoxamine

Luvox, Luvox CR

Fosinopril

Monopril

Fosphenytoin

Cerebyx

Furosemide

Lasix

Gabapentin

Neurontin

Gatifloxacin

Tequin

Gemfibrozil

Lopid

Gemifloxacin mesylate

Factive

Gentamicin

Garamycin

Glatiramer acetate

Copaxone

Glimepiride

Amaryl

Glimepiride-pioglitazone hydrochloride

Duetact

Glimepiride-rosiglitazone maleate

Avandaryl

Glipizide

Glucotrol

Glyburide

DiaBeta, Glynase, Micronase

Glyburide-metformin HCl

Glucovance

Griseofulvin

Fulvicin P/G, Grifulvin, Gris-PEG

Haloperidol

Haldol

Hexachlorophene

pHisoHex

Hydralazine-hydrochlorothiazide

Hydra-Zide

Hydrochlorothiazide

HydroDIURIL, Microzide, Oretic

Hydrochlorothiazide-fosinopril

Monopril HCT

Hydrochlorothiazide-irbesartan

Avalide

Hydrochlorothiazide-lisinopril

Prinzide, Zestoretic

Hydrochlorothiazide—losartan potassium

Hyzaar

Hydrochlorothiazide-methyldopa

Aldoril

Hydrochlorothiazide-metoprolol tartrate

Lopressor HCT

Hydrochlorothiazide-moexipril

Uniretic

Hydrochlorothiazide-propranolol

Inderide

Hydrochlorothiazide-quinapril

Accuretic

Hydrochlorothiazide-spironolactone

Aldactazide

Hydrochlorothiazide-telmisartan

Micardis HCT

Hydrochlorothiazide-timolol

Timolide

Hydrochlorothiazide-triamterene

Dyazide, Maxide

Hydrochlorothiazide-valsartan Hydroflumethiazide

Diovan HCT

Hydroxocobalamin

Cyanokit Antidote

Hydroxychloroquine

Plaquenil

Hypericum

Kira, St. John's wort

Hypericum-vitamin B1-vitamin C-kava-kava

One-A-Day Tension & Mood

Ibuprofen

Motrin

Imatinib Mesylate

Gleevec

Imipramine

Tofranil

Imiquimod

Aldara

Indapamide

Lozol

Interferon alfa-2b, recombinant

Intron A

Interferon alfa-n3 (human leukocyte derived)

Alferon-N

Interferon beta-1a

Avonex

Interferon beta-1b

Betaseron

Irbesartan-hydrochlorothiazide

Avalide

Isocarboxazid

Marplan

Isoniazid-pyrazinamide-rifampin

Rifater

Isotretinoin

Accutane, Amnesteem

Itraconazole

Sporanox

Ketoprofen

Orudis, Oruvail

Lamotrigine

Lamictal

Leuprolide acetate

Lupron, Lupron Depot

Levamisole

Levamisole

Levofloxacin

Levaquin

Levofloxacin-5% dextrose

Levaquin Injection

Lisinopril

Prinivil, Zestril

Lisinopril-hydrochlorothiazide

Prinzide, Zestoretic

Lomefloxacin

Maxaquin

Loratadine

Claritin

Loratadine-pseudoephedrine

Claritin-D

Losartan

Cozaar

Losartan-hydrochlorothiazide

Hyzaar

Lovastatin

Altoprev, Mevacor

Lovastatin-niacin

Advicor

Maprotiline

Ludiomil

Mefenamic acid

Ponstel

Meloxicam

Mobic

Mesalamine

Pentasa

Methazolamide

Glauctabs, Neptazane

Methotrexate

Trexall

Methoxsalen

8-MOP, Oxsoralen, Uvadex

Methyclothiazide

Enduron

Methyldopa-hydrochlorothiazide

Aldoril

Metolazone

Mykrox, Zaroxolyn

Metoprolol succinate

Toprol-XL

Metoprolol tartrate

Lopressor

Minocycline

Dynacin, Minocin, Solodyn

Mirtazapine

Remeron

Moexipril

Univasc

Moexipril-hydrochlorothiazide

Uniretic

Moxifloxacin

Avelox

Nabilone

Cesamet

Nabumetone

Relafen

Nadolol-bendroflumethiazide

Corzide

Nalidixic acid

Neggram

Naproxen

Naprosyn, EC-Naprosyn

Naproxen sodium

Anaprox, Anaprox DS, Naprelan

Naratriptan

Amerge

Nefazodone

Serzone

Nifedipine

Adalat CC, Procardia

Nisoldipine

Sular

Norfloxacin

Noroxin

Nortriptyline

Pamelor

Ofloxacin

Floxin

Olanzapine

Zyprexa

Olanzapine-fluoxetine

Symbyax

Olmesartan medoxomil-hydrochlorothiazide

Benicar HCT

Olsalazine

Dipentum

Omeprazole-sodium bicarbonate

Zegerid

Oxaprozin

Daypro

Oxcarbazepine

Trileptal

Oxycodone

Roxicodone

Oxytetracycline

Terramycin

Panitumumab

Vectibix

Pantoprazole

Protonix

Paroxetine hydrochloride

Paxil

Paroxetine mesylate

Pexeva

Pastinaca sativa

Parsnip

Pentosan polysulfate

Elmiron

Pentostatin

Nipent

Perphenazine

Trilafon

Pilocarpine

Salagen

Piroxicam

Feldene

Polymyxin B sulfate-trimethoprim sulfate

Polytrim

Polythiazide

Renese

Polythiazide-prazosin

Minizide

Porfimer sodium

Photofrin

Pramipexole dihydrochloride

Mirapex

Pravastatin

Pravachol

Pregabalin

Lyrica

Prochlorperazine

Compazine, Compro

Promethazine

Phenergan

Protriptyline

Vivactil

Pyrazinamide

Pyrazinamide

Pyrimethamine-sulfadoxine

Fansidar

Quetiapine

Seroquel

Quinapril

Accupril

Quinapril-hydrochlorothiazide

Accuretic

Quinidine gluconate

Quinidine

Quinidine sulfate

Quinidex

Rabeprazole sodium

Aciphex

Ramipril

Altace

Rasagiline mesylate

Azilect

Riluzole

Rilutek

Risperidone

Risperdal, Risperdal Consta

Ritonavir

Norvir

Rizatriptan

Maxalt, Maxalt-MLT

Ropinirole

Requip

Rosuvastatin

Crestor

Ruta graveolens

Rue

Saquinavir mesylate

Invirase

Selegiline

Eldepryl, Emsam

Sertraline

Zoloft

Sibutramine

Meridia

Sildenafil

Viagra

Simvastatin

Zocor

Simvastatin-ezetimibe

Vytorin

Sirolimus

Rapamune

Somatropin

Serostim

Sotalol

Betapace, Betapace AF

Sulfamethoxazole-trimethoprim

Bactrim, Septra

Sulfasalazine

Azulfidine

Sulfisoxazole acetyl

Gantrisin Pediatric

Sulindac

Clinoril

Sumatriptan

Imitrex

Tacrolimus

Prograf, Protopic

Tazarotene

Tazorac

Telmisartan-hydrochlorothiazide

Micardis HCT

Tetracycline

Sumycin

Thalidomide

Thalomid

Thioridazine hydrochloride

Thioridazine HCI

Thiothixene

Navane

Tiagabine

Gabitril

Tigecycline

Tygacil

Tolazamide

Tolinase

Tolbutamide

Orinase

Topiramate

Topamax

Tretinoin

Avita, Retin-A

Triamcinolone acetonide

Azmacort Inhalation

Triamterene

Dyrenium

Triamterene-hydrochlorothiazide

Dyazide, Maxzide

Trifluoperazine

Trifluoperazine

Trimipramine

Surmontil

Trovafloxacin

Trovan

Valacyclovir

Valtrex

Valdecoxib

Bextra

Valproate

Depacon

Valproic acid

Depakene

Valsartan-hydrochlorothiazide

Diovan HCT

Vardenafil

Levitra

Varenicline tartrate

Chantix

Venlafaxine

Effexor, Effexor XR

Verteporfin

Visudyne

Vinblastine

Velban

Voriconazole

Vfend

Zalcitabine

Hivid

Zaleplon

Sonata

Ziprasidone

Geodon

Zolmitriptan

Zomig

Zolpidem

Ambien, Ambien CR

Reference

LaGow B, ed. Drug Topics Red Book. Montvale, N.J.: Thomson Healthcare; 2009.