Class: Vaccine, Inactivated, Viral
Dosage Forms. Solution for Intramuscular or Subcutaneous Injection: 0.5 mL; also available in combination with other pediatric vaccines
Common FDA Label Indication, Dosing, and Titration.
1. Prevention of poliomyelitis: Children, one dose IM or sq at 2, 4, and 6-18 mo of age, and a booster at age 4-6 y as primary series
1. Prevention of poliomyelitis, in adults previously vaccinated but who are at risk for polio exposure: One dose IM or sq
Drug Characteristics: Poliovirus Vaccine, Inactivated
Medication Safety Issues: Poliovirus Vaccine, Inactivated
Drug Interactions: Poliovirus Vaccine, Inactivated
Adverse Reactions: Poliovirus Vaccine, Inactivated
Efficacy Monitoring Parameters. Prevention of poliomyelitis.
Toxicity Monitoring Parameters. Syncope.
Key Patient Counseling Points. Return to provider for each dose in the series.
Clinical Pearls. Adults, even those without evidence of previous immunization, rarely need poliovirus vaccine. A single dose is needed only if exposure likely, such as travel to an endemic area (eg, Pakistan, Nigeria). US has been polio-free since 1994.