Top 300 Pharmacy Drug Cards

TRAVOPROST: Travatan Z

Class: Prostaglandin, Antiglaucoma Agent

Dosage Forms. Ophthalmic Solution: 0.004%

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Common FDA Label Indication, Dosing, and Titration.

1. Ocular hypertension: 1 drop in affected eyes daily in the evening

2. Open-angle glaucoma: 1 drop in affected eyes daily in the evening

Off-Label Uses. None

MOA. Travoprost is a prostaglandin F 2-alpha analog. It is believed to reduce intraocular pressure by increasing the outflow of aqueous humor. Studies suggest that the main mechanism of action is increased uveoscleral outflow, but the exact mechanism is unknown.

Drug Characteristics: Travoprost

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Medication Safety Issues: Travoprost

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Drug Interactions: Travoprost. None known

Adverse Reactions: Travoprost

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Efficacy Monitoring Parameters. Reduction in intraocular pressure.

Toxicity Monitoring Parameters. Seek medical attention if symptoms of ocular irritation are severe.

Key Patient Counseling Points. Wash your hands and remove contact lenses before using the medicine. For administration, lie down or tilt your head back. With your index finger, pull down the lower lid of your eye to form a pocket. Hold the dropper close to your eye with the other hand. Drop the correct number of drops into the pocket made between your lower lid and eyeball. Gently close your eyes. Place your index finger over the inner corner of your eye for 1 min. Do not rinse or wipe the dropper or allow it to touch anything, including your eye. Put the cap on the bottle right away. Do not exceed once-daily dosing (may decrease efficacy). Separate administration of other ophthalmic agents by at least 5 min.

Clinical Pearls. Advise patients that there is a risk of permanent increased iris pigmentation associated with instillation of this product. May change length and number of eye lashes.