Dosage Forms. Suspension for Intramuscular Injection: For adults, available in combination with tetanus and diphtheria toxoids (Tdap); for Children, available in combination with tetanus and diphtheria toxoids (DTaP), and in combination with other pediatric vaccines
Common FDA Label Indication, Dosing, and Titration.
1. Prevention of diphtheria: Children, all infants at age 2, 4, 6 and 12-15 mo, and a fifth dose at age 4-6 y, as primary series of DTaP; Adults, at age 11-12 y, Tdap.
Off-Label Uses. None
Drug Characteristics: Diphtheria Toxoid
Medication Safety Issues: Diphtheria Toxoid
Drug Interactions: Diphtheria Toxoid
Adverse Reactions: Diphtheria Toxoid
Efficacy Monitoring Parameters. Prevention of diphtheria, although antibody concentrations might be measured; routine measurement for vaccine response is not recommended.
Toxicity Monitoring Parameters. None.
Key Patient Counseling Points. Return to provider for each dose in the series.
Clinical Pearls. Use the same brand of vaccine to complete the entire series, if possible.