Top 300 Pharmacy Drug Cards

DIPHTHERIA TOXOID: Daptacel, Adacel, Boostrix

Class: Vaccine

Dosage Forms. Suspension for Intramuscular Injection: For adults, available in combination with tetanus and diphtheria toxoids (Tdap); for Children, available in combination with tetanus and diphtheria toxoids (DTaP), and in combination with other pediatric vaccines

Common FDA Label Indication, Dosing, and Titration.

1. Prevention of diphtheria: Children, all infants at age 2, 4, 6 and 12-15 mo, and a fifth dose at age 4-6 y, as primary series of DTaP; Adults, at age 11-12 y, Tdap.

Off-Label Uses. None


Drug Characteristics: Diphtheria Toxoid


Medication Safety Issues: Diphtheria Toxoid


Drug Interactions: Diphtheria Toxoid


Adverse Reactions: Diphtheria Toxoid


Efficacy Monitoring Parameters. Prevention of diphtheria, although antibody concentrations might be measured; routine measurement for vaccine response is not recommended.

Toxicity Monitoring Parameters. None.

Key Patient Counseling Points. Return to provider for each dose in the series.

Clinical Pearls. Use the same brand of vaccine to complete the entire series, if possible.