Medical Physiology, 3rd Edition

References

Books and Reviews

Alper SL, Sharma AK. The SLC26 gene family of anion transporters and channels. Mol Aspects Med. 2013;34:494–515.

Arroyo JP, Kahle KT, Gamba G. The SLC12 family of electroneutral cation-coupled chloride cotransporters. Mol Aspects Med. 2013;34:288–298.

Binder HJ, Sandle GI. Electrolyte transport in the mammalian colon. Johnson LR. Physiology of the Gastrointestinal Tract. 3rd ed. Raven Press: New York; 1994:2133–2172.

Donowitz M, Ming Tse C, Fuster D. SLC9/NHE gene family, a plasma membrane and organellar family of Na+/H+ exchangers. Mol Aspects Med. 2013;34:236–251.

Farthing MJG. Oral rehydration therapy. Pharmacol Ther. 1994;64:477–492.

Field M, Semrad CE. Toxigenic diarrheas, congenital diarrheas, and cystic fibrosis: Disorders of intestinal ion transport. Annu Rev Physiol. 1993;55:631–655.

Greger R, Bleich M, Leipziger J, et al. Regulation of ion transport in colonic crypts. News Physiol Sci. 1997;12:62–66.

Kaunitz JD, Barrett KE, McRoberts JA. Electrolyte secretion and absorption: Small intestine and colon. 2nd ed. JB Lippincott: Philadelphia; 1995:326–361. Yamada T. Textbook of Gastroenterology. vol 1.

Montrose MH, Keely SJ, Barrett KE. Electrolyte secretion and absorption. Small intestine and colon. 4th ed. Lippincott Williams & Wilkins: Philadelphia; 2003:308–340. Yamada T. Textbook of Gastroenterology. vol. 1.

Palacin M, Estevez R, Bertran J, Zorzano A. Molecular biology of mammalian plasma membrane amino acid transporters. Physiol Rev. 1998;78:969–1054.

Rao MC. Oral rehydration therapy: New explanations for an old remedy. Annu Rev Physiol. 2004;66:385–417.

Zachos NC, Tse M, Donowitz M. Molecular physiology of intestinal Na/H exchange. Annu Rev Physiol. 2005;67:411–443.

Journal Articles

Canessa CM, Horisberger J-D, Rossier BC. Epithelial sodium channel related to proteins involved in neurodegeneration. Nature. 1993;361:467–470.

Knickelbein RG, Aronson PS, Schron CM, et al. Sodium and chloride transport across rabbit ileal brush border. II. Evidence for Cl-HCO3 exchange and mechanism of coupling. Am J Physiol. 1985;249:G236–G245.

Moseley RH, Hoglund P, Wu GD, et al. Downregulated in adenoma gene encodes a chloride transporter defective in congenital chloride diarrhea. Am J Physiol. 1999;276:G185–G192.

Schulz S, Green CK, Yuen PST, Garbers DL. Guanylyl cyclase is a heat-stable enterotoxin receptor. Cell. 1990;63:941–948.

Singh SK, Binder HJ, Boron WF, Geibel JP. Fluid absorption in isolated perfused colonic crypts. J Clin Invest. 1995;96:2373–2379.

 

SMALL INTESTINE

LARGE INTESTINE

Length (m)

6

2.4

Area of apical plasma membrane (m2)

~200

~25

Folds

Yes

Yes

Villi

Yes

No

Crypts or glands

Yes

Yes

Microvilli

Yes

Yes

Nutrient absorption

Yes

No

Active Na+ absorption

Yes

Yes

Active K+ secretion

No

Yes