PREGNANCY RECOMMENDATION: Compatible—Maternal Benefit >> Embryo–Fetal Risk
BREASTFEEDING RECOMMENDATION: No Human Data—Probably Compatible
BCG vaccine is a live, attenuated bacteria vaccine used to provide immunity to tuberculosis (1). Animal reproduction studies have not been conducted with the vaccine. The risk to the fetus from maternal vaccination is unknown. Because it is a live preparation, the CDC recommends that it not be used in pregnancy (2).
No reports describing the use of BCG vaccine in human lactation have been located. However, there does not appear to be any risk to a nursing infant if the mother receives the vaccine (2).
1.American Hospital Formulary Service. Drug Information 1997. Bethesda, MD: American Society of Health-System Pharmacists, 1997:2569–72.
2.CDC. Guidelines for Vaccinating Pregnant Women. Available at http://www.cdc.gov/vaccines/pubs/preg-guide.htm. Accessed May 16, 2010.